June 8, 2023 | Pharmaceuticals
Chronic pain affects millions of people worldwide, and conventional treatments such as nonsteroidal anti-inflammatory drugs (NSAIDs) and opioids have limitations due to their adverse effects and potential for addiction. Sustained release (SR) formulations of pain medications offer an alternative approach to managing chronic pain with reduced dosing frequency, improved compliance, and decreased side effects.
People prefer to go for medications once their pain begins however taking medicines often is not an appropriate option. Only one thing which may prove beneficial in pain management over extended periods of activity or overnight can get benefitted from sustained release drugs. This sounds like poetry to people suffering from chronic pain and looking to get relief at a more constant level throughout the day.
Benefits of Sustain release drugs
Sustain-release drugs can help in escaping the pain easing tremendously which remains one of its main benefits. On the other hand, if an immediate-release drug has been used, there may be a huge shift in pain alleviation, immediately after which there can be a sharp fall of pain when the effect of the pain goes off. There may be more chance of having pain which enforces frequent dosage practice.
Sustained release formulations typically use drug delivery systems that release the medication slowly and continuously, providing prolonged therapeutic effects. These systems can be designed to release the medication over a period of hours, days, or even weeks. The benefits of SR formulations include a lower risk of drug abuse, improved patient outcomes, and reduced healthcare costs.
For example, opioids such as oxycodone and morphine can be administered in SR formulations using various technologies, including matrix tablets, reservoir systems, or transdermal patches. These technologies release the medication at a controlled rate, minimizing the risk of overdose, addiction, and other adverse effects associated with immediate-release formulations.
Non-opioid analgesics such as gabapentin and pregabalin are also available in SR formulations, which provide constant therapeutic levels of the medication and reduce fluctuations in blood concentration. This results in better pain control and reduced side effects, such as dizziness and sedation.
In conclusion, Sustained release formulations offer a promising option for chronic pain management, addressing the limitations of conventional treatments while improving patient outcomes. Pharmaceutical Contract manufacturers keep on working to explore the efficacy and safety of these formulations and to develop new technologies that offer even better pain control and reduced risks for patients with chronic pain.
Akums Drugs and Pharmaceuticals Ltd.
Akums Drugs and Pharmaceuticals Ltd. is one of the known competent pharmaceutical contract manufacturers having WHO-GMP certification and known to be one of the consistent and continuous suppliers or manufacturers of sustain-release drugs or medications. Owing to the best quality, they can cater to a major chunk of requirements for Sustain release drugs.
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