Advancing Ophthalmic Care Through Innovation, Precision & Global Manufacturing Excellence
The ophthalmic market continues to evolve with growing demand for preservative-free formulations, advanced drug delivery systems, and stringent quality standards. At Akums, we combine scientific expertise with advanced sterile manufacturing technologies to develop high-quality ophthalmic products.
Our dedicated Ophthalmic Manufacturing Facility is equipped to manufacture a wide range of sterile eye care products under controlled aseptic conditions. Backed by robust quality systems and regulatory expertise, we support pharmaceutical companies from product development through commercial manufacturing with a focus on safety, sterility, and consistent quality.
Our manufacturing capabilities span multiple ophthalmic dosage forms and advanced drug delivery systems, enabling customers to address diverse therapeutic and commercial requirements.
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Form-Fill-Seal (FFS) Technology
Designed for high-speed, high-volume sterile manufacturing, our Form-Fill-Seal technology integrates container formation, aseptic filling, and sealing into a single continuous process. This minimizes human intervention, reduces contamination risk, and enhances manufacturing efficiency.
Key Advantages- Fully integrated aseptic manufacturing process
- Reduced contamination risk
- High-volume commercial manufacturing
- Consistent product quality
- Enhanced operational efficiency
- Suitable for unit-dose ophthalmic preparations
UNIMS® Unit-Dose Delivery System
Our UNIMS® technology provides convenient single-use ophthalmic packaging designed to improve patient safety and dosing accuracy. The unit-dose presentation eliminates repeated exposure to external contaminants while delivering the precise quantity of medication required for each application.
Benefits- Single-use sterile delivery
- Preservative-free compatibility
- Reduced contamination risk
- Improved patient compliance
- Accurate dosing
- Enhanced portability and convenience
Preservative-Free Vials
Growing clinical preference for preservative-free ophthalmic products has increased demand for specialized manufacturing capabilities.
Our facility supports sterile manufacturing of preservative-free ophthalmic formulations that improve ocular comfort while reducing preservative-related toxicity and irritation associated with long-term therapy.
These products are particularly suitable for chronic ophthalmic treatments and patients with sensitive eyes.
Three-Piece Eye Drop Systems
Akums manufactures conventional multidose ophthalmic solutions and suspensions using advanced aseptic filling technologies and high-quality packaging systems. These dosage forms offer flexibility across multiple therapeutic categories while ensuring product stability, dosing convenience, and regulatory compliance.
Suitable for:- Sterile ophthalmic solutions
- Ophthalmic suspensions
- Lubricating eye drops
- Anti-infective therapies
- Anti-inflammatory products
- Glaucoma medications
Innovation is central to our ophthalmic development strategy. Our proprietary formulation technologies enable pharmaceutical companies to overcome formulation challenges while improving product differentiation and patient outcomes.
PRIBSYS™ Technology
PRIBSYS™ is an advanced ionic-buffered preservative technology that eliminates the need for Benzalkonium Chloride (BKC)—one of the most widely used preservatives in ophthalmic formulations. By replacing conventional preservative systems, PRIBSYS™ enhances ocular tolerability while minimizing preservative-induced irritation and toxicity.
Technology Benefits- BKC-free preservation
- Improved ocular comfort
- Reduced preservative-related irritation
- Better patient tolerability
- Suitable for chronic ophthalmic therapies
- Enhanced product differentiation
e-Sol™ Technology
Many ophthalmic APIs possess poor aqueous solubility, making suspension formulations the conventional choice. e-Sol™ technology enables the conversion of ophthalmic suspensions into elegant, clear solutions, improving patient experience while enhancing therapeutic performance.
Key Advantages- Enhanced corneal penetration
- Improved drug bioavailability
- Better patient comfort
- Reduced ocular irritation
- Uniform dosing
- Elegant solution appearance
Aqua Nano Micellar™ Technology
Aqua Nano Micellar™ technology utilizes nano-sized micelles to encapsulate poorly soluble active pharmaceutical ingredients, enabling their effective dispersion within aqueous ophthalmic formulations. This innovative approach improves formulation stability while enhancing drug delivery and patient experience.
Platform Benefits- Improved solubilization of poorly soluble APIs
- Nano-sized drug encapsulation
- Enhanced formulation stability
- Improved ocular drug delivery
- Better therapeutic performance
- Expanded formulation possibilities
Purpose-Built for Sterile Ophthalmic Manufacturing
Every ophthalmic product is manufactured within highly controlled sterile environments designed to ensure product quality, sterility, and regulatory compliance.
The facility integrates advanced engineering systems with validated aseptic manufacturing processes to deliver consistent, high-quality ophthalmic formulations.
Water for Injection (WFI)-based manufacturing systems
Aseptic filling under Laminar Air Flow (LAF)
Validated double sterile filtration systems
Automated Cleaning-In-Place (CIP) systems
Automated Sterilization-In-Place (SIP) systems
Controlled cleanroom manufacturing environments
Sterile primary packaging components
Validated environmental monitoring systems
Integrated contamination control strategy
Quality Built Into Every Stage
Quality is embedded throughout the product lifecycle—from formulation development and raw material qualification to commercial manufacturing and final product release. Our quality systems ensure every batch consistently meets predefined specifications for sterility, safety, efficacy, and regulatory compliance.
Beyond manufacturing, Akums serves as an integrated development partner for ophthalmic products. Our multidisciplinary teams support customers throughout the product lifecycle, enabling faster development timelines and smoother regulatory pathways.
Development Services
- Formulation development
- Process optimization
- Analytical method development
- Technology transfer
- Process validation
- Scale-up studies
- Exhibit batch manufacturing
- Commercial manufacturing
Regulatory Support
- Dossier preparation
- Technical documentation
- Regulatory compliance support
- Global market filing assistance
- Product lifecycle management
Every ophthalmic program is unique. Our collaborative development model enables flexible engagement tailored to the technical, regulatory, and commercial requirements of each partner.
We work closely with customers to deliver solutions that accelerate development while ensuring quality and manufacturing excellence.
At Akums, we are committed to advancing ophthalmic healthcare through innovation, scientific excellence, and uncompromising quality. Every formulation manufactured at our ophthalmic facility reflects our focus on patient safety, regulatory compliance, technological advancement, and manufacturing precision. From concept to commercialization, we empower our partners with reliable manufacturing solutions that support successful product launches across domestic and international markets.
Why Innovation Matters in Ophthalmics
Modern ophthalmic therapies demand more than sterility—they require enhanced patient comfort, improved drug delivery, preservative-free solutions, and differentiated formulations that improve treatment outcomes.
By combining proprietary technology platforms with advanced sterile manufacturing capabilities, Akums helps pharmaceutical companies create next-generation ophthalmic products that address these evolving healthcare needs.
Let’s Shape the Future of
Ophthalmic Care—Together.
Whether you're developing preservative-free eye drops, advanced ophthalmic solutions, unit-dose therapies, or novel ocular drug delivery systems, Akums offers the scientific expertise, sterile manufacturing infrastructure, and global regulatory capabilities to help bring your vision to life.