General Introduction
The pharma industry is growing its prospect at an exponential rate. In this expansion of the industry, the crucial role of Contract Development and Manufacturing Organisations (CDMOs) can never be underestimated. They are the support system of the pharma industry. With the increased spread of diseases, its role is becoming more crucial and significant. Designing, manufacturing, and supplying of a drug undergoes many stages of testing and trial which further results in a high rate of failures in new drug development. On average, only one in five thousand discovery compounds will hit the market. If the situation gets analyzed, it will be discovered that maximum failures or unsuccessful trials are due to drug toxicity, safety, and efficacy issues. Reports suggest that a valid increase in the percentage of a new chemical object with poor physical, chemical, and biopharmaceutical properties in the drug pipeline has been considered in combination with those failure rates.
Oral Administration of Drugs
Oral management of drugs is still the most popular and main way of direction as it has many advantages. Easy management, high patient compliance, and reasonable costs are some of its advantages. Oral drug consumption is channelized simply, as once the drug is consumed it gets dissolved in gastrointestinal fluids before getting absorbed into the blood and reaching its place or site of action to provide relief. Reports suggest that nearly 40 percent of already discovered drugs or medications and 90 percent of the drugs which are yet to come on the market or in process of development are found to be badly or poorly solvable drugs. Poor solubility can further lead to low bioavailability resulting in suboptimal drug delivery, ineffective drug efficacy, and side effects. The poor solubility drugs never qualify for the standardized tests meant for them resulting in heavy losses and expenses to the manufacturing firms. This is one of the important reasons why companies look to shoulder their responsibilities with
Contract Development and Manufacturing Organisations (CDMOs).
Various drug delivery technologies to overcome these issues like nanotechnologies have been discovered which require vigilant, specialized, and dedicated endeavors. The old-defined methodologies for manufacturing drugs are not sufficient to create completely soluble drugs whereas Contract
Development and Manufacturing Organisations (CDMOs) are known to bring the desired results by incorporating innovative technologies required to bring or improve the solubility, dissolution, and bioavailability of drugs.
Role of CDMOs
CDMOs are well equipped and well versed to manufacture the best quality drugs that are effective, efficient, and safe in all respects. They assist the manufacturing firms to give the best yield in terms of medications and provide a wide array of services to pharma companies i.e., drug development and clinical supply, marketable active pharmaceutical ingredient (API), drug manufacturing and packing.
Akums Drugs and Pharmaceuticals Ltd.
Akums Drugs and Pharmaceuticals Ltd. is a globally renowned WHO-GMP certified and one of the principal Contract development and manufacturing pharmaceutical companies that focus on manufacturing and marketing of pharmaceutical drugs. The firm is known for its capacity to offer world-class services in all its business endeavors. Being a technologically driven firm, it remains ahead of time and updated with the best of skills, methodologies, and processes. Quality is the synonym used for Akums in the pharmaceutical Industry.
Key Takeaways
- Contract Development and Manufacturing Organisations (CDMOs) have played a crucial role in the expansion of the pharmaceutical industry.
- CDMOs are well-equipped to manufacture the best quality drugs which are effective, efficient, and safe in all respects.
- Akums Drugs and Pharmaceuticals Ltd. is a globally renowned WHO-GMP certified and one of the principal Contract development and manufacturing pharmaceutical companies that focuses on manufacturing and marketing of pharmaceutical drugs.
